Mesangial Deposits

Electron microscopy of a biopsy specimen in a patient with IgA nephropathy. Electron dense deposits can be identified in the mesangium (black arrows), which on immunofluorescence would have predominant or…

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Perihilar FSGS

Perihilar variant of focal segmental glomerulosclerosis (FSGS). Hyaline deposition and sclerosis occur at the vascular pole of the glomerulus. This variant is believed to be a secondary form of FSGS,…

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Glomerulomegaly

A normal glomerulus (left) and hypertrophied glomerulus (glomerulomegaly, right). Glomerulomegaly is an adaptive response to decreased nephron number (e.g. prematurity) and/or increased demand (e.g. obesity). Patients with glomerulomegaly may have…

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Rickets

Early radiographic changes on left knee X-ray in an infant with hypophosphatemic rickets. There is decreased mineralization of the long bones and splaying, or widening, at the distal femur and…

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WBC casts

WBC casts (black arrows) in a biopsy specimen of a patient with acute interstitial nephritis. Images courtesy of Patrick Walker, MD.

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Simple renal cysts

Microscopic renal cysts. Note the flattened to cuboidal epithelium lining the cysts. Images courtesy of Patrick Walker, MD.

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Crescents

A segmental (left, black arrow) and circumferential crescent (right) in a patient with IgA nephropathy. Images courtesy of Patrick Walker, MD.

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