Archive for June 5, 2020
Crescents
A segmental (left, black arrow) and circumferential crescent (right) in a patient with IgA nephropathy. Images courtesy of Patrick Walker, MD.
Read MoreEndocapillary hypercellularity
A normal appearing glomerulus (left) compared to a glomerulus with endocapillary hypercellularity (right). Note the hypercellular capillary loop (red arrow) compared to the normal capillary lumens (black arrows). This histologic…
Read MoreImmunofluorescent staining in C3 glomerulopathy
Immunofluorescent staining pattern in a patient with C3 glomerulopathy. There is strong C3 staining in the capillary loops and mesangium. Immunoglobulin staining, such as IgG, is typically absent or at…
Read MoreDense deposit disease
Dense deposit disease on electron microscopy in a patient with C3 glomerulopathy. This lesion results from intramembranous transformation of the glomerular basement membrane by sausage-like, “osmiophilic” dense material. Images courtesy…
Read MoreMembranoproliferative glomerulonephritis
Membranoproliferative pattern of glomerular injury in a patient with C3 glomerulopathy. This pattern of injury typically has endocapillary proliferation, diffuse capillary wall thickening, increased mesangial matrix, and mesangial proliferation visible…
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