Simple renal cysts

Microscopic renal cysts. Note the flattened to cuboidal epithelium lining the cysts. Images courtesy of Patrick Walker, MD.

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Crescents

A segmental (left, black arrow) and circumferential crescent (right) in a patient with IgA nephropathy. Images courtesy of Patrick Walker, MD.

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Endocapillary hypercellularity

A normal appearing glomerulus (left) compared to a glomerulus with endocapillary hypercellularity (right). Note the hypercellular capillary loop (red arrow) compared to the normal capillary lumens (black arrows). This histologic…

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Dense deposit disease

Dense deposit disease on electron microscopy in a patient with C3 glomerulopathy. This lesion results from intramembranous transformation of the glomerular basement membrane by sausage-like, “osmiophilic” dense material. Images courtesy…

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Membranoproliferative glomerulonephritis

Membranoproliferative pattern of glomerular injury in a patient with C3 glomerulopathy. This pattern of injury typically has endocapillary proliferation, diffuse capillary wall thickening, increased mesangial matrix, and mesangial proliferation visible…

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Foam Cells

Clusters of interstitial foam cells (arrows) in a kidney biopsy. These are commonly found in biopsy specimens of patients with Alport syndrome, FSGS, IgA nephropathy, and other proteinuric kidney diseases.…

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