General COVID-19 Updates
Upcoming ISN-IPNA Webinar: ‘COVID-19 and the Kidney: interesting differences and similarities between children and adults’ Wednesday, July 1, 9-10 EST
Registration information: https://register.gotowebinar.com/register/7727495670521621771?source=IPNA
ASN Webinar: AKI: the Kidney/Lung Connection and Fluid Management in COVID-19
- CDC: Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with Coronavirus Disease 2019 (COVID-19)
- European Centre for Disease Prevention and Control: Paediatric Inflammatory Multisystem Syndrome and SARS-Co-V-2 Infection in Children
- CDC COCA call: Multisystem Inflammatory Syndrome in Children associated with Coronavirus Disease 2019
- Multisystem inflammatory syndrome in children with COVID-19. ASN Podcast
- Multisystem inflammatory syndrome in children (MIS-C) interim guidance. AAP Guidance: Paediatric Multisystem Inflammatory Syndrome Temporally Associated with COVID-19- Royal College of Paediatrics and Child Health
- Preliminary Assessment of AKI in critically Ill Children Associated with SARS-CoV02 Infection. Bjornstad et al, CJASN.
COVID-19 Vaccine Information
General articles on mRNA vaccines
Information for Dialysis Centers
Link to ASN dialysis webinar from 4/2/20 (PDF of slide sis also available on this site)
The Children's Hospital Association Hosted a Webinar Presented by the CDC on Preparing Dialysis Units for Covid-19
CDC Dialysis Recommendations: Interim additional guidance for infection prevention and control recommendations for patients with suspected or confirmed COVID-19 in outpatient hemodialysis facilities: https://www.cdc.gov/coronavirus/2019-ncov/healthcare-facilities/dialysis.html
American Society of Nephrology- COVID-19 Information for Providers of Dialysis Service- webinar:
Webinar Recording Available: COVID-19 Informational Webinar for Providers of Dialysis Services
On March 11, 2020, ASN conducted an informational webinar focusing on new COVID-19 guidance for dialysis facilities from CDC and a presentation on managing patients with COVID-19 who require dialysis. This 60-minute webinar explored the possible implications for patients receiving renal replacement therapy and the staff who care for them. The webinar featured presentations from Shannon Novosad, MD, of CDC, and Suzanne Watnick, MD, FASN, and Liz McNamara, MN, RN, of Northwest Kidney Centers.
The webinar recording and slides have been posted on the NTDS website, which also has links to all updated materials from CDC.
ASN COVID-19 AKI Webinar (featuring Dr. Goldstein)
Full webinar available at: https://www.asn-online.org/covid-19/
Kidney Transplant Information
From American Society for Transplantation for transplant recipients: Coronavirus disease 2019: frequently asked questions.
American Society of Transplantation: COVID-19: FAQs for Organ Transplantation (geared more towards transplant providers): https://www.myast.org/sites/default/files/COVID19%20FAQ%20Tx%20Centers%20030220-1.pdf
US Department of Health and Human Services: Information for transplant programs and OPOs regarding 2019 novel Coronavirus: https://optn.transplant.hrsa.gov/news/information-for-transplant-programs-and-opos-regarding-2019-novel-coronavirus/
Association of organ procurement organizations: COVID-19 bulletin (information regarding organ procurement) https://www.aopo.org/information-about-covid-19-coronavirus-is-being-released-rapidly-we-will-post-updates-as-we-receive-them/
Please see the UNOS website for updates regarding making patients temporarily inactive due to COVID-19, and temporarily inactivating your program’s waiting less if you will be unable to provide transplant services in the coming weeks or months
American Society of Transplant Surgeons COVID-19 Strike Force (recommendations surrounding prioritizing transplants)
Research and Commentary Articles
Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China (Dong at al, Pediatrics)
Epidemiology and Clinical Features of Coronavirus 2019 in Children, Choi et al, Clinical and Experimental Pediatrics
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents: A Systemic Review. Castagnoli et al, JAMA Pediatrics
Children with Covid-19 in Pediatric Emergency Departments in Italy- Parri et al, NEJM
General Information: COVID-19 and the Kidneys
Kidney Disease in the Time of COVID-19: Major challenges to Patient Care, Rabb, The Journal of Clinical Investigation
How COVID-19 has Changed the Management of Glomerular Diseases. Bomback et al, CJASN
AKI in Pediatric Inflammatory Multisystem Syndrome temporally associated with severe acute respiratory syndrome coronavirus-2 pandemic: experience from PICUs across United Kingdom. Deep et al. Critical Care Medicine
Renal Transplant/Immunosuppressed Patients
Successful recovery of covid-19 pneumonia in a renal transplant recipient with long-term immunosuppression (only 1 adult patient, but there is very limited data on this topic)
Hypertension/Renin-Angiotensin-Aldosteron System Inhibitors
Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Covid-19, Vaduganathan et al, NEJM
Coronavirus Disease 2019 (COVID-19) Infection and Renin Angiotensin System Blockers, Bavishi C et al, JAMA Cardiology
Hydroxychloroquine and Azithromycin as a Treatment of COVID-19: Results of an Open-Label Non-Randomized Clinical Trial, Gautret P et al. International Journal of Antimicrobial Agents
Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19), A review, Sanders et al, JAMA
Health Disparities and COVID-19
Resources for Return to School
Return to School for Pediatric Solid Organ Transplant Recipients in the United States During the COVID-19 Pandemic: Expert Opinion on Key Considerations and Best Practices. Journal of the Pediatric Infectious Diseases Society. Downes et al.
Collections of Articles
Research Projects that are Enrolling COVID-19 Positive Pediatric Nephrology Patients
Research project through ERKNet on behalf of Dr. Kjell Tullus and Dr. Marina Vivarelli
We have launched a global study where we invite all paediatric nephrologist in the world to include data from anonymized children with COVID-19.
From Dr. McBryde at the NIH:
This is another de-idenitfied registry of children with COVID-19:
‘The website for the registry is: https://www.pedscovid19registry.com/. The site contains information on the provision of de-identified data, IRB oversight, and case report forms for data submission. There are, I believe, information related to authorship guidelines, as well.
While the data is heavily focused on pediatric malignancies, the data collection form does include children who are immunosuppressed and have a number of organ system diseases, including renal disorders. Hopefully, this registry will be a good first step to describing COVID-19 in pediatric patients, and provide some hypothesis generation for future investigations into specific disorders and medication exposures.
ASPN Workforce Committee Webinar: Telemedicine - Covid-19 Updates, March 26, 2020
- Sample Language & Sample Physical Exam for Telehealth Visits
- Relevant Video from the American Academy of Pediatrics regarding Telehealth and Covid-19
- Telemedice Best Practices from Riley Children's Hospital
AAP Webinar on Telehealth (19 minutes):
General Workforce Issues
AAP CME Offer: In the midst of the COVID-19 crisis, the AAP is expanding its online education to all members. Pedialink, the AAP's online education portal, is offering all courses free of charge to all levels of membership for the time being. Login at Pedialink. On the Continuing Education tab, go to CME Finder and choose online courses. Any member can choose a course from this list where they can register through ShopAAP at no charge.
Recommendations for home BP monitoring (with many thanks to Dr. Tammy Brady):
Each of the following 3 home devices has strengths and weaknesses, but all were tested in children and passed the testing. Information about the validation testing is below
Welch Allyn ProBP2000: tested in 35 children as part of a larger study, used K4 as diastolic
Omron: tested in almost 200 children, but the participants were normotensive and the validation protocol used was less stringent
A&D: tested in 85 children with a reasonable protocol, grade B for SBP, grade A for DBP
This video describes preparing an individual for blood pressure measurement:
Patient and family handouts from the Action learning Network (primarily focused towards children with heart disease or heart transplant, but very relevant to children with kidney disease)