ASPN has been actively monitoring the developments related to COVID-19 and the emerging - outbreaks - within the United States - and elsewhere. - We are committed to the health and wellbeing of our membership and the patients and families you serve.
The PAS 2020 meeting has been cancelled due to the coronavirus pandemic. - The PAS program office should communicate directly with you about hotel reservations (which should be automatically canceled if you made a reservation through the PAS website) and refunding your conference fee if you have already registered for the meeting.
Members of our Clinical Affairs Committee have put together pertinent guidance below, on caring for renal patients. - - This will be placed and updated on the ASPN Website.
General Family Information: AAP
CDC: Resources for higher risk individuals
European Society for Pediatric Nephrology COVID-19 Resources
NephJC COVID-19 Information, with links to transplant and pediatric information
CDC MMWR: Coronavirus 2019 in Children- United States, February 12-April 2, 2020
Upcoming ISN-IPNA Webinar: COVID-19 and the Kidney: interesting differences and similarities between children and adults Wednesday, July 1, 9-10 EST
Registration information: - https://register.gotowebinar.com/register/7727495670521621771?source=IPNA
ASN Webinar: AKI: the Kidney/Lung Connection and Fluid Management in COVID-19
Protecting civil rights during COVID-19. - ASN podcast
COVID-19 Toolkit for Nephrology Clinicians: Preparing for a Surge. - ASN
Multisystem inflammatory syndrome in children (MIS-C) interim guidance. - AAP
MISC
- CDC: Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with Coronavirus Disease 2019 (COVID-19)
- European Centre for Disease Prevention and Control: Paediatric Inflammatory Multisystem Syndrome and SARS-Co-V-2 Infection in Children
- CDC COCA call: Multisystem Inflammatory Syndrome in Children associated with Coronavirus Disease 2019
- Multisystem inflammatory syndrome in children with COVID-19. - ASN Podcast
- Multisystem inflammatory syndrome in children (MIS-C) interim guidance. - AAP Guidance: Paediatric Multisystem Inflammatory Syndrome Temporally Associated with COVID-19- Royal College of Paediatrics and Child Health
- Preliminary Assessment of AKI in critically Ill Children Associated with SARS-CoV02 Infection. - Bjornstad et al, CJASN.
COVID-19 Vaccine Information
CDC: What every clinician should know about COVID-19 vaccine safety (COCA call recording)
AAP COVID 19 Vaccine frequently asked questions
CDC: Learn about the new mRNA COVID-19 vaccine
CHOP Vaccine education center: Questions and answers about COVID-19 vaccines
AAP. - Interim guidance for COVID-19 vaccination in children and adolescents
General articles on mRNA vaccines
Developing mRNA-vaccine technologies. - Schlake et al. - RNA biology. - 2012
mRNA vaccine delivery using lipid nanoparticles. - Reichmuth et al. - Therapeutic Delivery. - 2016.
Information for Dialysis Centers
Link to ASN dialysis webinar from 4/2/20 (PDF of slide sis also available on this site)
The Children's Hospital Association Hosted a Webinar Presented by the CDC on Preparing Dialysis Units for Covid-19
CDC Dialysis Recommendations: Interim additional guidance for infection prevention and control recommendations for patients with suspected or confirmed COVID-19 in outpatient hemodialysis facilities: https://www.cdc.gov/coronavirus/2019-ncov/healthcare-facilities/dialysis.html
American Society of Nephrology- COVID-19 Information for Providers of Dialysis Service- webinar:
Slides: https://www.asn-online.org/g/blast/files/ASN_COVID-19_webinar_combined_slides_03.11.2020_Final.pdf
Webinar: https://www.asn-online.org/ntds/
Webinar Recording Available: COVID-19 Informational Webinar for Providers of - Dialysis Services
On March 11, 2020, ASN conducted an informational webinar focusing on new COVID-19 guidance for dialysis facilities from CDC and a presentation on managing patients with COVID-19 who require dialysis. This 60-minute webinar explored the possible implications for patients receiving renal replacement therapy and the staff who care for them. The webinar featured presentations from Shannon Novosad, MD, of - CDC, and Suzanne Watnick, MD, FASN, and Liz McNamara, MN, RN, of Northwest Kidney Centers.
The webinar recording and slides - have been posted on the NTDS website, which also has links to all updated materials from CDC.
ASN COVID-19 AKI Webinar (featuring Dr. Goldstein)
Full webinar available at: https://www.asn-online.org/covid-19/
Kidney Transplant Information
From American Society for Transplantation for transplant recipients: Coronavirus disease 2019: frequently asked questions.
American Society of Transplantation: COVID-19: FAQs for Organ Transplantation (geared more towards transplant providers): https://www.myast.org/sites/default/files/COVID19%20FAQ%20Tx%20Centers%20030220-1.pdf
US Department of Health and Human Services: Information for transplant programs and OPOs regarding 2019 novel Coronavirus: https://optn.transplant.hrsa.gov/news/information-for-transplant-programs-and-opos-regarding-2019-novel-coronavirus/
Association of organ procurement organizations: COVID-19 bulletin (information regarding organ procurement) https://www.aopo.org/information-about-covid-19-coronavirus-is-being-released-rapidly-we-will-post-updates-as-we-receive-them/
Please see the UNOS website for updates regarding making patients temporarily inactive due to COVID-19, and temporarily inactivating your programu2019s waiting less if you will be unable to provide transplant services in the coming weeks or months
UNOS Webinar: Organ Donation and Transplant Town Hall
UNOS website: rCOVID-19 Transplant Refusal Codes
American Society of Transplant Surgeons COVID-19 Strike Force (recommendations surrounding prioritizing transplants)
UCSF: COVID-10 Frequently Asked Questions for Pediatric Immunocompromised Host Clinicians
The Transplantation Society COVID-19 Dashboard
The Transplantation Society Global Transplantation Covid Report March 2020
NephJC Covid-19 Transplant Info
The Transplantation Societyu2019s Transplant Infectious Disease Update on COVID-19
American Society of Transplantation COVID-19 FAQs
UNOS: COVID-19 Weekly Organ Recovery and Usage MAP (RUM)
UNOS: Covid-19 News and Resources for Transplant Patients
AST Recommendations and Guidance for Organ Donor Testing
ASN COVID-19 Transplant Webinar from 4/23/20
Research and Commentary Articles
Epidemiology/Pediatric Disease
The Novel Coronavirus 2019 Epidemic and Kidneys (Naicker et al, Kidney International)
Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China (Dong at al, Pediatrics)
Covid-19 in children: initial characterization of the pediatric disease
Epidemiology and Clinical Features of Coronavirus 2019 in Children, Choi et al, Clinical and Experimental Pediatrics
Detection of Covid-19 in Children in Early January 2020 in Wuhan, China, - Liu et al. NEJM
Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized with COVID-19 in the New York City Area. - Richardson et al. - JAMA
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents: A Systemic Review. - Castagnoli et al, JAMA Pediatrics
Children with Covid-19 in Pediatric Emergency Departments in Italy- Parri et al, NEJM
Coinfection and Other Clinical Characteristics of COVID-19 in Children. - Wu et al. Pediatrics -
General Information: COVID-19 and the Kidneys
Kidney Disease in the Time of COVID-19: Major challenges to Patient Care, - Rabb, The Journal of Clinical Investigation
Early Description of Coronavirus 2019 Disease in Kidney Transplant Recipients in New York, JASN
How COVID-19 has Changed the Management of Glomerular Diseases. - Bomback et al, CJASN
Renal Involvement and Early Prognosis in Patients with COVID-19 Pneumonia. - Pei at al, JASN
Acute Kidney Injury in Patients Hospitalized with COVID-19. Jirsch et al, Kidney International
Pediatric COVID-19-Associated Rhabdomyolysis: A Case Report. - Gefen et al. - Pediatric Nephrology
COVID-19 in Patients with Kidney Disease. - Ajaimy et al, CJASN
Acute kidney injury in COVID-19: emerging evidence of a distinct pathophysiology. Batlle et al. JASN
Kidney biopsy findings in patients with COVID-19. - Kudose et al. - JASN
AKI in COVID-19 associated MIS-C. - Lipton et al, Kidney 360
Renal Transplant/Immunosuppressed Patients
Successful recovery of covid-19 pneumonia in a renal transplant recipient with long-term immunosuppression (only 1 adult patient, but there is very limited data on this topic)
COVID-19: A Global Transplant Perspective on Successfully Navigating a Pandemic
Outpatient Management of the Kidney Transplant Recipient During the SARS-CoV-2 Virus Pandemic
The Severity of COVID-19 in Children on Immunosuppressive Medication, Marlais et al, The Lancet
Organ Procurement and Transplantation During the COVID-19 Pandemic, Loupy et al, The Lancet
Presentation and Outcomes of Patients with ESKD and COVID-19. Valeri et al, JASN
The Immunocompromised Transplant Recipient and SARS-CoV-2 Infection. - Fishman. - JASN.
Presentation and outcomes of patients with ESKD and COVID-19. Valeri et al. JASN
Dialysis
Epidemiology of COVID-19 in an Urban Dialysis Center. - Corbett et al. - JASN
Hypertension/Renin-Angiotensin-Aldosteron System Inhibitors
Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Covid-19, - Vaduganathan et al, NEJM
Coronavirus Disease 2019 (COVID-19) Infection and Renin Angiotensin System Blockers, Bavishi C et al, JAMA Cardiology
NEPHJC Website - Peer Reviewed Information Regarding ACEI/ARB
Therapies
Hydroxychloroquine and Azithromycin as a Treatment of COVID-19: Results of an Open-Label Non-Randomized Clinical Trial, - Gautret P et al. International Journal of Antimicrobial Agents
Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19), A review, Sanders et al, JAMA
Multicenter Initial Guidance on Use of Antivirals for Children with COVID-19/SARS-CoV-2
Remdesivir in Patients with Acute or Chronic Kidney Disease and COVID-19. - Adamsick et al, JASN
COVID-19 and Calcineurin Inhibitors: Should They Get Left Out in the Storm? Willicombe et al, JASN.
Remdesivir in patients with acute or chronic kidney disease and COVID-19. Adamsick et al. JASN
Health Disparities and COVID-19
COVID-19, racism, and racial disparities in kidney disease. Crews et al. JASN
Racial/Ethnic and Socioeconomic Disparities of SARS-CoV-2 Infection Among Children. - Goyal et al, Pediatrics - - - - - - - - -
Resources for Return to School
Returning to school during COVID-19- healthychildren.org
COVID-19 and children with medical complexity ECHO (extension for community health outcomes) AAP
State school reopening plans. - AAP
COVID-19 planning considerations: guidance for school reentry. - AAP
COVID-19 transmission and children: the child is not to blame. - Lee, Raszca, Pediatrics
COVID-19 in schools- the experience in NSW
CDC Back to school decision making tool
Collections of Articles
NEJMu2019s Journal Watch COVID-19 Summaries
JAMA Networku2019s COVID-19 Coverage
AAPu2019s Red Book Online COVID-19
Research Projects that are Enrolling COVID-19 Positive Pediatric Nephrology Patients
Research project through ERKNet on behalf of Dr. Kjell Tullus and Dr. Marina Vivarelli
We have launched a global study where we invite all paediatric nephrologist in the world to include data from anonymized children with COVID-19.
The survey can be accessed here.
From Dr. McBryde at the NIH:
This is another de-idenitfied registry of children with COVID-19:
u2018The website for the registry is: https://www.pedscovid19registry.com/. The site contains information on the provision of de-identified data, IRB oversight, and case report forms for data submission. There are, I believe, information related to authorship guidelines, as well.
While the data is heavily focused on pediatric malignancies, the data collection form does include children who are immunosuppressed and have a number of organ system diseases, including renal disorders. Hopefully, this registry will be a good first step to describing COVID-19 in pediatric patients, and provide some hypothesis generation for future investigations into specific disorders and medication exposures.
Telemedicine/Billing/Coding
CMS End-stage Renal Disease Provideru2019s Toolkit
COVID-19 Telehealth Coding and Billing Practice Management Tips
Renal Physicians Association Guidance on Billing and Coding for Remote Nephrology Services
ASPN Workforce Committee Webinar: Telemedicine - Covid-19 Updates, March 26, 2020
- Q&A
- Slides
- Sample Language & Sample Physical Exam for Telehealth Visits -
- Relevant Video from the American Academy of Pediatrics regarding Telehealth and Covid-19
- Telemedice Best Practices from Riley Children's Hospital
AAP Compiled List of State Regulations
AAP Webinar on Telehealth (19 minutes):
CMS toolkit u2013 General Nephrology
Renal Physicians Association guidance on remote billing and coding
Summary of CMS Interim Final Rules on Billing
AAMC: Tools for Clinical Teaching via Telehealth
Center for Connected Health Policy: Quick Glance State Telehealth Actions in Response to COVID-19
ASPN: ESRD Provider Telehealth and Telemedicine Took Kit
General Workforce Issues
AMA: Article on Caring for our Caregivers during COVID
AAP CME Offer: In the midst of the COVID-19 crisis, the AAP is expanding its online education to all members. Pedialink, the AAP's online education portal, is offering - all - courses free of charge to - all - levels of membership for the time being. Login at - Pedialink. On the Continuing Education tab, go to CME Finder and choose online courses. Any member can choose a course from this list where they can register through ShopAAP at no charge.
Wellness Resources
Headspace app u2013 free for medical professionals
Hypertension
Recommendations for home BP monitoring (with many thanks to Dr. Tammy Brady):
Each of the following 3 home devices has strengths and weaknesses, but all were tested in children and passed the testing. - Information about the validation testing is below
Welch Allyn ProBP2000: tested in 35 children as part of a larger study, used K4 as diastolic
Omron: tested in almost 200 children, but the participants were normotensive and the validation protocol used was less stringent
A&D: tested in 85 children with a reasonable protocol, grade B for SBP, grade A for DBP
https://www.stridebp.org/bp-monitors
This video describes preparing an individual for blood pressure measurement:
https://www.youtube.com/watch?v=T9J3RE4Eins&feature=youtu.be
Renin-angiotensin system blockers and the COVID-19 pandemic (Hypertension)
Patient Information/Wellness
Patient and family handouts from the Action learning Network (primarily focused towards children with heart disease or heart transplant, but very relevant to children with kidney disease)
COVID-19 Mental Health Resources
National Kidney Foundation Website
National Kidney Foundation patient handout- resources for patients with kidney disease -
AAP Webinar: Resilience in Stressful Times and Connecting During Times of Trauma (20 minutes)
Resident/Fellow Education
Teaching Resources for Nephrology Fellows
Teaching Hospitals, Teaching Physicians and Medical Residents: CMS Flexibilities to Fight COVID-19